Monday, October 2, 2023

Covid-19: Nobel Prize Winners -- October 2, 2023

Locator: 45626COVID.

Updates

October 5, 2023:  

The WSJ article on the Nobel Prize. One word: baloney.  Unless he's a fly on the wall, he has no clue what the Nobel Prize committees are doing.

The WSJ article on the Nobel Prize. Outstanding article. 

 

For me? The big takeaway — how incredibly amazing this country is. It would be interesting to see the long list of folks nominated for the various “science” Nobel Prizes.
The Fields Medal (for Math) is awarded every four years. It was last awarded last year, 2022. Of the last twenty winners, only seven were “from the US.”
The Nobel Prize for literature this year went to a Norwegian.
“Research" in math and literature, unlike research in physics, medicine, and chemistry, do not require any lab support. Research in the sciences does not require lab support per se, but generally speaking, lab support is needed to prove or disprove purported advances in PM&C.

Original Post

Global:

  • Tech: Israel. 
  • Medicine: US. 2023 Nobel — both from Penn State.
  • Physics: US. 2023 Nobel — one of three — Ohio State.
  • Chemistry: US
  • Literature:
  • Peace: woke

Biggest story today: Nobel Prize in medicine. It's good to see some standards still hold. This was an incredibly important "statement."

Katalin Karikó (Hungarian: Karikó Katalin; born 17 January 1955) is a Hungarian-American biochemist who specializes in RNA-mediated mechanisms, particularly in vitro-transcribed mRNA for protein therapies. Karikó laid the scientific groundwork for mRNA vaccines against major obstacles and scepticism in the scientific community. Karikó co-founded and was CEO of RNARx from 2006 to 2013. Since 2013, she has been associated with BioNTech RNA Pharmaceuticals, first as a vice president and promoted to senior vice president in 2019. She was also an adjunct professor at the University of Pennsylvania. She later became a professor at the University of Szeged in Hungary.

Drew Weissman (born September 7, 1959 is an American physician-scientist and Nobel Prize laureate best known for his contributions to RNA biology. His work, which won him a Nobel Prize in medicine in 2023, helped enable development of mRNA vaccines, the best known of which are those for COVID-19 produced by BioNTech/Pfizer and Moderna. Weissman is the inaugural Roberts Family Professor in Vaccine Research, director of the Penn Institute for RNA Innovation, and professor of medicine at the Perelman School of Medicine at the University of Pennsylvania (Penn). He and his research colleague Katalin Karikó have received numerous awards including the presigious Lasker-DeBakey Clinical Medical Research Award. He received the 2023 Nobel Prize in Physiology or Medicine together with Karikó "for their discoveries concerning nucleoside base modifications that enabled the development of effective mRNA vaccines against COVID-19."

Why was this so important? For our children: the iGen, the Z gen, the Alpha Gen. Especially our daughters and granddaughters.

From my "Covid library." I have to go back to these two books.

Moonshot: Inside Pfizer's Nine-Month Race to Make the Impossible Possible, Dr Albert Bourla, Chairman and CEO, Pfizer, c. 2022. 

The Vaccine: Inside The Race to Conquer the Covid-19 Pandemic, Joe Miller with Dr Özlem Türeci and Dr Uğur Şahin, c. 2022. Link here.

EVs -- Deliveries -- Forecast -- October 2, 2023

Locator: 45625AUTOS.

Pick-up trucks: by state -- Texas does not make top ten list -- link here: 

Prediction: one hundred percent of all Americans in the upper 10% income bracket will own/lease three cars/pickup trucks, one of which will be an EV by 2035. One hundred percent of all Texans in the upper 10% income bracket will have a Ford pickup truck by 2035.

Rivian: in round numbers, Rivian will ship about 50,000 vehicles in calendar year 2023. Link here. Here are the numbers. OMG.

Tesla: deliveries miss estimates. In round numbers Tesla shipped about 435,000 vehicles in 3Q23.

*************************
Asteroid City

One of the most interesting things about Asteroid City: so little foreshadowing. And something almost no one else has commented on.

Let's google my statement that there was so little foreshadowing in Asteroid City:

When I sat down to see his latest film "Asteroid City," I was very curious how the credits would look, given that 21 names appear on the film's poster alone.
What I loved about the opening credits is that every actor is billed along with their character name. One, in particular, stood out to me. It was in the ending "and" position, but it was not given that credit. It simply said, "Jeff Goldblum as the alien."
You see those five words together and become immediately jazzed. Not only was I anxious to see one of our most idiosyncratic performers play a Wes Andersonian alien, I was surprised they let us know that information so soon into the movie.
Also, from the review:
Renowned acting teacher Konstantin Stanislavski once said, "There are no small parts, only small actors," and Wes Anderson understands that better than almost any other filmmaker working today.

On another note, irony: very little time on screen, big actor, the movie was all about Marlon Brando and yet he barely appeared onscreen, huge role, small onscreen presence. Apocalypse Now.  Director unable to "control" Brando. Wes Anderson completely controls his productions.

Surge -- October 2, 2023

 Locator: 45624TECH.
 Locator: 45623NVDA.

Gasoline Prices -- Los Angeles -- October 2, 2023

Locator: 45623LA.

Link here.

CATL, EVs, And All That Jazz -- October 2, 2023

 Locator: 45622EVS.

Update -- Much More To The Story

Link to Forbes.

The chairs of the three most powerful House committees have threatened to subpoena Ford if it does not provide documents detailing a deal with China’s CATL battery maker. Ford cannot ignore this request, and it might even force them to back out of the deal. It’s already pressed pause on a new $3.5 billion battery plant in Michigan.

It’s not clear what Ford will do after this, but the experience illustrates how turbulent the electric vehicle (EV) transition might be.

In 2021, President Biden announced an executive order that directs government policies to ensure 50% of all new passenger vehicle sales are electric by 2030. This year, the administration proposed that the figure increase to two-thirds by 2032. These are ambitious targets—the electric vehicle (EV) share of the new vehicle market was just 7% for the first half of this year. Getting from 7% to 67% by 2032 in a commercially viable way is going to take a massive reallocation of people, capital, and resources.

Such a monumental transition would be challenging even in the best of times. Today’s EVs are powered by lithium-ion batteries. Coupling and growing the two industries together comes with many challenges, including investing in new capital equipment, forming new business ventures, licensing the know-how, and ensuring they have the right people in place.

Mining and processing the raw materials for these batteries so far has largely been done outside of the United States. Ford found a way to domestically manufacture EVs by licensing battery cell technology from China’s CATL, a world leader in lithium iron phosphate battery technology. The arrangement was announced in February 2023 and allowed for Ford’s wholly owned subsidiary in Michigan to manufacture the battery cells using CATL’s LFP battery cell knowledge and services. In other words, Ford will control a 100% ownership stake in the plant while licensing the know-how.

Now, congressional concerns over CATL’s ties to the Chinese Communist Party have led to the subpoena, and Ford has halted work at the Michigan battery factory. It’s unclear if they will resume.

Original Post -- Some Weeks Ago

Ford halts construction of $3.5 billion EV battery plant in Michigan:

  • why Barron's says this is a big, big deal; link here; link here, also;
  • "Michigan" can't be happy
  • how many union jobs lost or "put on hold"?
  • Ford re-thinking this EV thing?
  • UAW - Ford, GM, Stellantis -- circular firing squad
  • UAW planned / plans for months (plural)-long strike and will gradually expand